A muscular path to quiescence

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A muscular path to quiescence

A muscular path to quiescence uscle stem cells called satellite cells can pull back from the brink, according to Zammit et al. (page 347). When activated by muscle damage, the cells divide and start uniformly down a differentiation path. Only at the last minute do some of the cells split off to revert to a quiescent, stem cell phenotype. Satellite cells sit quietly underneath the basal lamina o...

متن کامل

On the path to a Duchenne muscular dystrophy therapy.

Duchenne Muscular Dystrophy (DMD) is a devastating inherited disease of children with no effective therapies. Here I discuss the landscape for new treatments and the history, current status and prospects for our work developing recombinant biglycan as DMD therapy.

متن کامل

Evidence-based path to newborn screening for Duchenne muscular dystrophy.

OBJECTIVE Creatine kinase (CK) levels are increased on dried blood spots in newborns related to the birthing process. As a marker for newborn screening, CK in Duchenne muscular dystrophy (DMD) results in false-positive testing. In this report, we introduce a 2-tier system using the dried blood spot to first assess CK with follow-up DMD gene testing. METHODS A fluorometric assay based upon the...

متن کامل

Escaping death to quiescence

Cancer recurrence is associated with treatment failure and is the main cause of death, 1 and thus remains to be a major clinical challenge. elevated level of the cyclin-dependent kinase 1 (CDK1) correlates with cancer recurrence and treatment resistance in patients with breast cancer or colorectal cancer. 2,3 it is proposed that defects in CDKs may lead to the accumulated genetic defects, which...

متن کامل

University revenue diversification: a path to financial stability

The purpose of present study was to investigate revenue diversification among Iranian public universities in order to improve the stability and flexibility of financial resources. A quantitative practical correlational research design was utilized for this study. The spatial scope of research was one and two level comprehensive public and industrial public universities during 2013-2018. Data we...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2004

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb1663iti1